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Insights Archive

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Compliance and Industry Update – November 2025

At ClearScript, we are committed to keeping you informed and prepared for the evolving landscape of Pharmacy Benefit Management (PBM). This update highlights key regulatory changes, industry updates, and ClearScript’s proactive strategies.

Go to: Compliance and Industry Update – November 2025
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Your Guide to Managing Trend in 2026

If you’re managing pharmacy benefits in 2026, you’re likely facing rising costs, new therapies, and tough decisions. So how do you stay ahead? It starts with understanding what drives trend and how to manage it with confidence.

Go to: Your Guide to Managing Trend in 2026
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DRUG SPOTLIGHT: Centanafadine

Centanafadine is a novel, first-in-class, non-stimulant under development for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children, adolescents, and adults.  It’s rapid onset & good safety profile would likely result in uptake for patients who do not respond to generic stimulant / non-stimulant therapy options.

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DRUG SPOTLIGHT: Yeztugo® (lenacapavir)

A new formulation of lenacapavir has been developed for preexposure prophylaxis (PrEP) against HIV-1 infection. Yeztugo provides protection with only two annual injections. Gilead is also in the process of developing a once-yearly formulation of Yeztugo.

Go to: DRUG SPOTLIGHT: Yeztugo® (lenacapavir)
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You Deserve More Than Reporting — And That’s Exactly What We Deliver

How ClearScript Partners With You to Improve Plan Performance, Not Just Measure It. At ClearScript, we’re proud to serve as more than just your pharmacy benefit manager. We’re your partner in navigating a complex and constantly evolving pharmacy landscape. And while robust reporting is a key part of our service, it’s only the beginning.

Go to: You Deserve More Than Reporting — And That’s Exactly What We Deliver